Datasets
| Source | Name | Most enriched gene sets | ||
|---|---|---|---|---|
| GTEx | Artery-Coronary | Mineral absorption, transcription regulatory region sequence-specific DNA binding, Zinc homeostasis, Circadian rhythm, zinc ion homeostasis, cellular response to zinc ion, Copper homeostasis, cellular transition metal ion homeostasis, cellular response to copper ion, negative regulation of growth | ||
| GTEx | Cells-EBV-transformedlymphocytes | |||
| GTEx | Brain-CerebellarHemisphere | response to unfolded protein, regulation of cellular response to heat, regulation of cellular response to stress, cellular response to unfolded protein, Protein processing in endoplasmic reticulum, chaperone mediated protein folding requiring cofactor, MAPK signaling pathway, regulation of inclusion body assembly, negative regulation of inclusion body assembly, Circadian rhythm related genes | ||
| GTEx | Liver | monocarboxylic acid biosynthetic process, Pyruvate metabolism, Histidine metabolism, Arginine and proline metabolism, Glycolysis / Gluconeogenesis, Tryptophan metabolism, Protein processing in endoplasmic reticulum, Tyrosine metabolism, Fatty Acid Omega Oxidation, organic substance transport | ||
| GTEx | Esophagus-Muscularis | Complement Activation, cellular transition metal ion homeostasis, muscle contraction, cellular divalent inorganic cation homeostasis, Human Complement System, cellular response to cytokine stimulus, cytokine-mediated signaling pathway, cellular zinc ion homeostasis, Copper homeostasis, zinc ion homeostasis | ||
| GTEx | Prostate | transcription regulatory region sequence-specific DNA binding, transcription corepressor binding, Circadian rhythm related genes, Circadian rhythm, RNA polymerase II core promoter proximal region sequence-specific binding, transcription regulatory region DNA binding, RNA polymerase II core promoter proximal region sequence-specific binding, sequence-specific double-stranded DNA binding, E-box binding, Exercise-induced Circadian Regulation | ||
| GTEx | Kidney-Cortex | transcription regulatory region sequence-specific DNA binding, Circadian rhythm related genes, regulation of fat cell differentiation, RNA polymerase II regulatory region DNA binding, positive regulation of fat cell differentiation, transcription corepressor binding, sequence-specific double-stranded DNA binding, transcription regulatory region DNA binding, Adipogenesis, core promoter binding | ||
| GTEx | Colon-Sigmoid | transcription cofactor binding, Adipogenesis, Folate Metabolism, transcription corepressor binding, photoperiodism, Nuclear Receptors Meta-Pathway, Mineral absorption, cellular zinc ion homeostasis, Circadian rhythm, transcription regulatory region sequence-specific DNA binding | ||
| GTEx | Adipose-Subcutaneous | integral component of plasma membrane, Copper homeostasis, cellular zinc ion homeostasis, cellular divalent inorganic cation homeostasis, Zinc homeostasis, zinc ion homeostasis, cellular response to type I interferon, cellular response to zinc ion, cellular transition metal ion homeostasis, negative regulation of viral life cycle | ||
| GTEx | Thyroid | entrainment of circadian clock by photoperiod, Circadian rhythm related genes, transcription cofactor binding, transcription regulatory region sequence-specific DNA binding, Circadian rhythm, Melatonin metabolism and effects, photoperiodism, transcription corepressor binding, transcription regulatory region DNA binding, sequence-specific double-stranded DNA binding | ||
| GTEx | Brain-Nucleusaccumbens(basalganglia) | core promoter binding, negative regulation of gene expression | ||
| GTEx | Esophagus-Mucosa | Circadian rhythm related genes, Circadian rhythm, transcription corepressor binding, transcription regulatory region sequence-specific DNA binding, Drug metabolism, Metabolism of xenobiotics by cytochrome P450, sequence-specific double-stranded DNA binding, photoperiodism, transcription cofactor binding, Retinol metabolism | ||
| GTEx | Spleen | transcription regulatory region sequence-specific DNA binding, Cytokine-cytokine receptor interaction, inflammatory response, cytokine-mediated signaling pathway, Systemic lupus erythematosus, photoperiodism, tertiary granule membrane, Circadian rhythm related genes, transcription corepressor binding, GPCRs, Class A Rhodopsin-like | ||
| GTEx | Esophagus-GastroesophagealJunction | photoperiodism, Circadian rhythm, Zinc homeostasis, transcription regulatory region sequence-specific DNA binding, Melatonin metabolism and effects, zinc ion homeostasis, cellular response to cytokine stimulus, Mineral absorption, Nuclear Receptors Meta-Pathway, transcription cofactor binding | ||
| GTEx | Lung | Zinc homeostasis, cellular response to zinc ion, cellular zinc ion homeostasis, Mineral absorption, cellular response to copper ion, cellular divalent inorganic cation homeostasis, negative regulation of growth, Influenza A, ficolin-1-rich granule, positive regulation of release of sequestered calcium ion into cytosol | ||
| GTEx | Brain-Hypothalamus | core promoter binding, negative regulation of gene expression, negative regulation of nucleic acid-templated transcription, regulation of transcription, DNA-templated, regulation of transcription from RNA polymerase II promoter, positive regulation of gene expression | ||
| GTEx | Testis | integral component of plasma membrane | ||
| GTEx | Artery-Tibial | zinc ion homeostasis, cellular zinc ion homeostasis, Mineral absorption, secretory granule lumen, Zinc homeostasis, cellular response to type I interferon, type I interferon signaling pathway, cellular response to zinc ion, Circadian rhythm, extracellular matrix organization | ||
| GTEx | AdrenalGland | transcription corepressor binding, Circadian entrainment, Circadian rhythm, Cytokine-cytokine receptor interaction, Exercise-induced Circadian Regulation, cytokine-mediated signaling pathway, histone H3 deacetylation, cytokine receptor activity, Huntington disease, organic hydroxy compound biosynthetic process | ||
| GTEx | Breast-MammaryTissue | Glutathione metabolism, cellular zinc ion homeostasis, Zinc homeostasis, zinc ion homeostasis, Mineral absorption, Oxidative Stress, cellular response to zinc ion, transition metal ion binding, cellular transition metal ion homeostasis, fatty-acyl-CoA biosynthetic process | ||
| GTEx | Brain-Putamen(basalganglia) | transcription regulatory region sequence-specific DNA binding, core promoter sequence-specific DNA binding, RNA polymerase II regulatory region DNA binding, negative regulation of transcription from RNA polymerase II promoter, regulation of blood vessel endothelial cell migration, regulation of apoptotic process, negative regulation of programmed cell death, regulation of intracellular signal transduction, regulation of nucleic acid-templated transcription, MAPK signaling pathway | ||
| GTEx | Brain-Hippocampus | core promoter binding, Circadian rhythm related genes, negative regulation of gene expression, negative regulation of nucleic acid-templated transcription | ||
| GTEx | Brain-Substantianigra | |||
| GTEx | Nerve-Tibial | Mineral absorption, cellular divalent inorganic cation homeostasis, negative regulation of growth, cellular zinc ion homeostasis, zinc ion homeostasis, Zinc homeostasis, cellular response to zinc ion, cellular transition metal ion homeostasis, Oxidative Stress, Folate Metabolism | ||
| GTEx | Brain-FrontalCortex(BA9) | response to unfolded protein, regulation of inclusion body assembly, negative regulation of inclusion body assembly, Hypothesized Pathways in Pathogenesis of Cardiovascular Disease, regulation of microtubule nucleation, C3HC4-type RING finger domain binding, protein tyrosine kinase binding, negative regulation of transcription from RNA polymerase II promoter in response to stress, Influenza A, MAPK signaling pathway | ||
| GTEx | MinorSalivaryGland | Exercise-induced Circadian Regulation, Circadian rhythm, sequence-specific double-stranded DNA binding, Melatonin metabolism and effects, Circadian rhythm related genes, entrainment of circadian clock by photoperiod, transcription regulatory region DNA binding, transcription regulatory region sequence-specific DNA binding, transcription corepressor binding, photoperiodism | ||
| GTEx | Pancreas | Circadian rhythm related genes, transcription regulatory region sequence-specific DNA binding, Circadian rhythm, transcription corepressor binding, RNA polymerase II core promoter proximal region sequence-specific binding, transcription regulatory region DNA binding, Nuclear Receptors Meta-Pathway, Circadian entrainment, RNA polymerase II regulatory region DNA binding, Metapathway biotransformation Phase I and II | ||
| GTEx | Colon-Transverse | Complement and coagulation cascades, Circadian rhythm, Melatonin metabolism and effects, regulation of endopeptidase activity, positive regulation of cell differentiation, Complement and Coagulation Cascades, photoperiodism, endopeptidase inhibitor activity, transcription regulatory region sequence-specific DNA binding, Exercise-induced Circadian Regulation | ||
| GTEx | Uterus | transcription regulatory region sequence-specific DNA binding, transcription corepressor binding, RNA polymerase II regulatory region DNA binding, Circadian rhythm related genes, sequence-specific double-stranded DNA binding, Circadian rhythm, transcription regulatory region DNA binding, Melatonin metabolism and effects, Exercise-induced Circadian Regulation, photoperiodism | ||
| GTEx | Adipose-Visceral(Omentum) | Nuclear Receptors Meta-Pathway, cytokine-mediated signaling pathway, zinc ion homeostasis, cellular response to zinc ion, cellular zinc ion homeostasis, Mineral absorption, response to lipopolysaccharide, neutrophil mediated immunity, Cytokine-cytokine receptor interaction, TNF signaling pathway | ||
| GTEx | Artery-Aorta | Hematopoietic cell lineage, cellular zinc ion homeostasis, zinc ion homeostasis, inflammatory response, cytokine-mediated signaling pathway, Zinc homeostasis, integral component of plasma membrane, cellular transition metal ion homeostasis, neutrophil activation involved in immune response, Mineral absorption | ||
| GTEx | Brain-Cortex | response to unfolded protein, chaperone mediated protein folding requiring cofactor, negative regulation of inclusion body assembly, cellular response to unfolded protein, Influenza A, Legionellosis, ficolin-1-rich granule lumen, neutrophil mediated immunity, regulation of microtubule nucleation, MAPK signaling pathway | ||
| GTEx | Skin-NotSunExposed(Suprapubic) | Zinc homeostasis, cellular zinc ion homeostasis, zinc ion homeostasis, cellular transition metal ion homeostasis, cellular response to copper ion, cellular response to zinc ion, Circadian rhythm related genes, Amino Acid metabolism, Mineral absorption, Tyrosine metabolism | ||
| GTEx | Vagina | Melatonin metabolism and effects, entrainment of circadian clock by photoperiod, Exercise-induced Circadian Regulation, transcription regulatory region sequence-specific DNA binding, transcription regulatory region DNA binding, Circadian rhythm, Circadian rhythm related genes, transcription corepressor binding, sequence-specific double-stranded DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding | ||
| GTEx | Brain-Spinalcord(cervicalc-1) | transcription corepressor binding, Circadian rhythm, Circadian rhythm related genes, transcription regulatory region sequence-specific DNA binding, core promoter sequence-specific DNA binding, negative regulation of endothelial cell migration, Ras signaling pathway, negative regulation of endothelial cell proliferation, core promoter binding, negative regulation of epithelial cell proliferation | ||
| GTEx | Skin-SunExposed(Lowerleg) | Zinc homeostasis, cellular response to zinc ion, zinc ion homeostasis, transcription regulatory region sequence-specific DNA binding, Folate Metabolism, Melatonin metabolism and effects, Circadian rhythm related genes, entrainment of circadian clock by photoperiod, Circadian rhythm, cellular zinc ion homeostasis | ||
| GTEx | Heart-AtrialAppendage | Circadian rhythm related genes, Circadian rhythm, cellular zinc ion homeostasis, cellular transition metal ion homeostasis, cellular response to zinc ion, transcription corepressor binding, photoperiodism, Zinc homeostasis, transcription regulatory region sequence-specific DNA binding, E-box binding | ||
| GTEx | Heart-LeftVentricle | negative regulation of viral life cycle, negative regulation of viral genome replication, cellular response to type I interferon, cytokine-mediated signaling pathway, Influenza A, NOD-like receptor signaling pathway, regulation of cytokine production, membrane repolarization during action potential, transcription regulatory region sequence-specific DNA binding, type I interferon signaling pathway | ||
| GTEx | Pituitary | Circadian rhythm related genes, transcription regulatory region sequence-specific DNA binding, Circadian rhythm, transcription corepressor binding, RNA polymerase II core promoter proximal region sequence-specific binding, RNA polymerase II regulatory region DNA binding, transcription regulatory region DNA binding, sequence-specific double-stranded DNA binding, Mammary gland development pathway - Puberty (Stage 2 of 4), Aldosterone-regulated sodium reabsorption | ||
| GTEx | Muscle-Skeletal | carboxylic acid transport, cellular response to cytokine stimulus, Transcription factor regulation in adipogenesis, cellular zinc ion homeostasis, Adipogenesis, Ectoderm Differentiation, cytokine-mediated signaling pathway, nitrogen compound transport, carboxylic acid transmembrane transporter activity, cation:cation antiporter activity | ||
| GTEx | Brain-Cerebellum | response to unfolded protein, negative regulation of inclusion body assembly, MAPK signaling pathway, Protein processing in endoplasmic reticulum, regulation of cellular response to stress, regulation of cellular response to heat, cellular response to heat, negative regulation of transcription from RNA polymerase II promoter in response to stress, cellular response to unfolded protein, chaperone mediated protein folding requiring cofactor | ||
| GTEx | Stomach | transcription corepressor binding, entrainment of circadian clock by photoperiod, Circadian rhythm related genes, Circadian rhythm, Melatonin metabolism and effects, photoperiodism, Exercise-induced Circadian Regulation, Selenium Micronutrient Network, secretory granule lumen, inflammatory response | ||
| GTEx | Brain-Amygdala | transcription regulatory region sequence-specific DNA binding, Protein processing in endoplasmic reticulum, core promoter sequence-specific DNA binding, RNA polymerase II regulatory region DNA binding, regulation of apoptotic process, negative regulation of cellular macromolecule biosynthetic process, positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-templated | ||
| GTEx | Ovary | photoperiodism, Circadian rhythm related genes, Circadian rhythm, transcription regulatory region sequence-specific DNA binding, Melatonin metabolism and effects, sequence-specific double-stranded DNA binding, transcription corepressor binding, transcription regulatory region DNA binding, Exercise-induced Circadian Regulation, Ectoderm Differentiation | ||
| GTEx | Brain-Anteriorcingulatecortex(BA24) | Circadian rhythm related genes, transcription corepressor binding, Circadian rhythm, transcription regulatory region sequence-specific DNA binding, E-box binding, core promoter binding, core promoter sequence-specific DNA binding, negative regulation of cellular macromolecule biosynthetic process, nuclear chromosome part, negative regulation of gene expression | ||
| GTEx | Brain-Caudate(basalganglia) | Circadian rhythm related genes, transcription regulatory region sequence-specific DNA binding, core promoter sequence-specific DNA binding, Influenza A, RNA polymerase II regulatory region DNA binding, positive regulation of intracellular signal transduction, nuclear body, negative regulation of nucleic acid-templated transcription, positive regulation of I-kappaB kinase/NF-kappaB signaling, cytokine-mediated signaling pathway | ||
| GTEx | SmallIntestine-TerminalIleum | Circadian rhythm, transcription regulatory region DNA binding, transcription corepressor binding, Circadian rhythm related genes, Melatonin metabolism and effects, transcription regulatory region sequence-specific DNA binding, entrainment of circadian clock by photoperiod, integral component of plasma membrane, sequence-specific double-stranded DNA binding, Exercise-induced Circadian Regulation | ||
| GTEx | Cells-Culturedfibroblasts |
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